Fluorinating Reagents Sodium Chlorodifluoroacetate CAS NO.1895-39-2

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Technology, Emden-Leer of Germany, etc. 

Company Name: Nantong Baokai Chemical Co., Ltd

Year Established: 2006

Main products: fluoro-pharmaceutical intermediates

1. Introduction of Sodium chlorodifluoroacetate (CAS No. 1895-39-2)

Our Sodium chlorodifluoroacetate products usually exists with the form of Sodium chlorodifluoroacetate 96%. This is one kind of white powder, usually with the package of 25kg/bag/paper drum. When comes to its storage, it is usually kept in a cool, dry, well-ventilated place (Ensure adequate ventilation during use). We provide the Sodium chlorodifluoroacetate 96% with Min. Order of 25Kilogram. Transportation of Sodium chlorodifluoroacetate: not hazardous product.

Sodium chlorodifluoroacetate is being stable under recommended storage conditions, and you should avoid strong oxidizing agents and moisture. Beside, the hazardous decomposition products formed under fire conditions, including Carbon oxides, Hydrogen chloride gas, Hydrogen fluoride, Sodium oxides.

Our Certificate Of Analysis (COA):

Our Package for 25 Kg:



2. Properties of Sodium chlorodifluoroacetate (CAS No. 1895-39-2)

Properties of Sodium chlorodifluoroacetate are as below: (1)ACD/LogP: 1.451; (2)ACD/LogD (pH 5.5): -2.28; (3)ACD/LogD (pH 7.4): -2.30; (4)ACD/BCF (pH 5.5): 1.00; (5)ACD/BCF (pH 7.4): 1.00; (6)ACD/KOC (pH 5.5): 1.00; (7)ACD/KOC (pH 7.4): 1.00; (8)#H bond acceptors: 2; (9)#H bond donors: 1; (10)#Freely Rotating Bonds: 1; (11)Polar Surface Area: 37.3; (12)Flash Point: 25.9 °C; (13)Enthalpy of Vaporization: 39.44 kJ/mol; (14)Boiling Point: 119.2 °C at 760 mmHg; (15)Vapour Pressure: 10.3 mmHg at 25°C.

3. The molecular structure of Sodium chlorodifluoroacetate (CAS No. 1895-39-2)

You can still convert the following datas into molecular structure:
(1)SMILES:[Na+].ClC(F)(F)C([O-])=O
(2)Std. InChI:InChI=1S/C2HClF2O2.Na/c3-2(4,5)1(6)7;/h(H,6,7);/q;+1/p-1
(3)Std. InChIKey:MRTAVLDNYYEJHK-UHFFFAOYSA-M

4. Safety Information of Sodium chlorodifluoroacetate (CAS No. 1895-39-2)

For being irritating to eyes and respiratory system, Sodium chlorodifluoroacetate may cause inflammation to the skin or other mucous membranes. Therefore, you should wear suitable protective clothing, gloves and eye/face protection. If in case of contact with eyes, rinse immediately with plenty of water and seek medical advice. While using it, remember to avoid contact with skin and eyes.

Below are some detailed cases and according measures:
(1). General advice:
Consult a physician. Show this safety data sheet to the doctor in attendance.
(2). If inhaled:
If breathed in, move person into fresh air. If not breathing give artificial respiration Consult a physician.
(3). In case of skin contact:
Wash off with soap and plenty of water. Consult a physician.
(4). In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
(5). If swallowed:
Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

5. Uses of Sodium chlorodifluoroacetate (CAS No. 1895-39-2)

biphenyl-2-carbaldehyde could react with Sodium chlorodifluoroacetate to produce 2-(2,2-difluoro-vinyl)-biphenyl. This reaction could happen with the reagent of Ph3P and solvent of bis-(2-methoxy-ethyl) ether, with the reaction time of 2 hour(s) and the reaction temperature of 160 °C. The yield is 53 %.

2,2,2-trifluoro-1-phenyl-ethanone could react with Sodium chlorodifluoroacetate to produce 1,1,3,3,3-pentafluoro-2-phenylpropene. This reaction could happen with the reagent of Ph3P and solvent of bis-(2-methoxy-ethyl) ether.