Pharmaceutical Intermediates 1,1,1-Trifluorobutan-2-one CAS NO.381-88-4

    we have a land of 3 hectares and an experienced R&D team.

    We establish closely cooperative relationships with Zhejiang University, Zhejiang University of Science and

Technology, Emden-Leer of Germany, etc. 

Company Name: Nantong Baokai Chemical Co., Ltd

Year Established: 2006

Main products: fluoro-pharmaceutical intermediates

1. Introduction of 1,1,1-Trifluoro-2-Butanone (CAS No. 381-88-4)

1,1,1-Trifluoro-2-Butanone, for being stable under recommended storage conditions, should be avoided away from heat, flames and sparks, extremes of temperature and direct sunlight. Besides, its hazardous decomposition products formed under fire conditions are including Carbon oxides, Hydrogen fluoride.
 

2. Properties of 1,1,1-Trifluoro-2-Butanone (CAS No. 381-88-4)

1,1,1-Trifluoro-2-Butanone has the following detailed property information: (1)ACD/LogP: 1.02; (2)# of Rule of 5 Violations: 0; (3)#H bond acceptors: 1; (4)#H bond donors: 0; (5)#Freely Rotating Bonds: 1; (6)Polar Surface Area: 17.07 Ų; (7)Index of Refraction: 1.313; (8)Molar Refractivity: 21.06 cm³; (9)Molar Volume: 108 cm³; (10)Polarizability: 8.35×10^-24cm³; (11)Surface Tension: 17.1 dyne/cm; (12)Density: 1.166 g/cm³; (13)Enthalpy of Vaporization: 28.94 kJ/mol; (14)Boiling Point: 45.4 °C at 760 mmHg; (15)Vapour Pressure: 349 mmHg at 25°C.

3. The molecular structure of Potassium chromium sulfate (CAS No. 7788-99-0)

You can still convert the following datas into molecular structure:
(1)SMILES: FC(F)(F)C(=O)CC
(2)InChI: InChI=1/C4H5F3O/c1-2-3(8)4(5,6)7/h2H2,1H3
(3)InChIKey: QBVHMPFSDVNFAY-UHFFFAOYAQ

4. Safety Information of 1,1,1-Trifluoro-2-Butanone (CAS No. 381-88-4)

Hazard Codes F,Xi
Risk Statements 11
Safety Statements 9-16-29-33
RIDADR UN 1993 3/PG 1
WGK Germany 3
Hazard Note Flammable
HazardClass 3
PackingGroup II

(1). Highly flammable. This chemical may catch fire in contact with air, only need brief contact with an ignition source, have a very low flash point or evolve highly flammable gases in contact with water.
(2). Irritant. This chemical may cause inflammation to the skin or other mucous membranes.

Following are some specific cases and the according meastures:
(1). If inhaled: If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
(2). In case of skin contact: Wash off with soap and plenty of water. Consult a physician.
(3). In case of eye contact: Flush eyes with water as a precaution.
(4). If swallowed: Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

5. Uses of 1,1,1-Trifluoro-2-Butanone (CAS No. 381-88-4)

1,1,1-Trifluoro-2-Butanone can be used to produce 3,3-dibromo-1,1,1-trifluoro-butan-2-one. This reaction will need reagents sodium acetate, acetic acid, bromine.

6. Package of 1,1,1-Trifluoro-2-Butanone (CAS No. 381-88-4)

(1). 1,1,1-Trifluoro-2-Butanone is packed with the 25KG (50KG，100KG，250KG) / barrel or lined plastic steel drum.
(2). 1,1,1-Trifluoro-2-Butanone could also be packed according to the customers' requirements.